How does one dissolve a brick in a beaker of water?
This is a question that James Pipkin, vice president of new product development at Ligand Pharmaceuticals and The University of Kansas answers in this interview.
Today’s cyclodextrin is a great story, case-study and learning opportunity about the rise of one of the most important players in the cyclodextrin industry.
Inspiring!
From Molecule to Market (lawrencebusinessmagazine.com)
Scientists create first mouse model with complete, functional human immunesystem and a human-like gutmicrobiome that is capable of mounting specific antibody responses.
Such a model would have unlimited uses in pharma development. The work of Paolo Casali et al groundbreaking and will disrupt the animal models we use for efficacy and safety studies. How would you use this model first? I imagine studies with vaccines probably…
Nature Immunology, 5 July 2024
Inspiring research and patent from our collaborators at Università degli Studi di Torino and Universidad de Murcia
Adrián Matencio Durán, Francesco Trotta, Yousef Khazaei Monfared, Fabrizio Caldera, and José Manuel López Nicolás disclosed an invention in which various cyclodextrins are investigated in the therapy of gout and hyperuricemia.
WO2024133757 CYCLODEXTRIN DERIVATIVES FOR THE TREATMENT OF GOUT AND HYPERURICEMIA (wipo.int)
Our next free webinar, titled “Cyclodextrin formulations: The Journey from the Benchtop to the Patients” brings together experts who will guide us through the milestones of this remarkable journey.
Event Overview: Join us for an illuminating webinar that traces the evolution of cyclodextrin-based drug delivery systems—from laboratory research to real-world patient care. Our esteemed speakers will explore key aspects of this journey, highlighting breakthroughs, challenges, and the promise of cyclodextrins in improving therapeutic outcomes.
Link for registration: https://www.congress-service.hu/rendezveny/cyclodextrinwebinar2024
Time&Date: September 26., 2024, 3 pm – 5 pm (CEST, Budapest time)
Agenda:
Who Should Attend: Researchers, clinicians, pharmaceutical professionals, and anyone curious about the journey of cyclodextrins—from lab discoveries to patient impact.
Don’t miss this opportunity to explore the bridge between science and healing. Register now and join the cyclodextrin revolution!
I would be delighted to hear suggestions for upcoming topics and engage in Q&A, so please feel free to add your impressions in the comments or via email at tamas.sohajda@carbohyde.com. Thank you.
In the coming weeks, we will continue focusing on using cyclodextrins as active ingredients, disease by disease. Stay tuned!
A small CarboHyde delegation (Kristóf Felegyi and Balázs Attila Kondoros) is just starting their Bicyclos HEurope secondment in Santiago de Compostella under the fantastic support of Angel Piñeiro & Rebeca Garcia-Fandino.
Hopefully this short time will be enough for the guys to learn the basics of molecular modeling and do some fancy cyclodextrin stuff on their own.
Kristóf Felegyi just completed CarboHyde’s very first secondment under the scope of the Bicyclos HEurope project under the strong support of Csenge Anna Felegyi-Tóth.
Kristof worked for 5 months in the lab of Jose Manuel Garcia Fernandez under the supervision of Juanma Benito and created various cyclodextrin polymers that we will evaluate for gene and small molecule delivery.
😎
We appreciate the strong support and hospitality of CSIC and look forward to further collaborations.
As Kristof did not take a single photo in the lab, we can only trust he did not only do sightseeing in the wonderful city
CarboHyde CEO Tamas Sohajda recently delivered a compelling presentation at the CPHI North America conference, focusing on innovative applications of cyclodextrins in the pharmaceutical industry. His talk highlighted how these unique cyclic oligosaccharides can enhance drug delivery, improve solubility, and stabilize formulations, offering significant benefits to pharmaceutical development.
Cyclodextrins, known for their ability to form inclusion complexes with various molecules, have been extensively studied for their potential to revolutionize drug formulations. Sohajda’s presentation delved into recent advancements and case studies demonstrating the successful integration of cyclodextrins in new drug delivery systems. These developments promise to improve the efficacy and safety of numerous medications, addressing longstanding challenges in drug formulation and bioavailability.
The talk received considerable attention from industry professionals, underscoring CarboHyde’s leading role in pioneering the use of cyclodextrins for pharmaceutical innovation. Attendees had the opportunity to engage with Sohajda, discussing cyclodextrin research’s practical applications and future directions.
A video of the event is available on CPHI website – after a registration – for those who missed the presentation or wish to revisit the insights shared.
CPHI: Lightning Round: Excipients 4.0 – Cyclodextrins (CDs) (video) (cphi-online.com)
On Vimeo:
Dr Tamas Sohajda Lightning Round Excipients 4.0 – Cyclodextrins CDs on Vimeo
Stay tuned for more updates from CarboHyde as they continue to push the boundaries of pharmaceutical technology.
Today’s #yclodextrin is about the fantastic progression of the GENEGUT project CarboHyde is part of.
The 5th in-person General Assembly meeting was kindly hosted by our partners at i3S – Instituto de Investigação e Inovação em Saúde, Bruno Sarmento, Catarina Leite Pereira in Porto, PT 🚀
We (Kristóf Felegyi) reported the chemistry work, which was our part, and now look forward to seeing how these building blocks will perform in RNA delivery and eventually in drug formulation. Caitriona O’Driscoll and Ana Francisca Soares presented some of the promising data at the 21st International Cyclodextrin Symposium last week.
We look forward to interesting discussions, progress updates and networking within the GENEGUT consortium 💡
We are extremely proud to share that our formulation expert, Balázs Attila Kondoros yesterday, successfully defended on PhD thesis (dealing with green, solvent-free) technologies for making cyclodextrin complexes at the University of Szeged mentored by Rita Ambrus and Ildiko Csoka.
Huge congratilations Balázs for the career milestone, we are honored to have you on the CarboHyde team!
In a few days the global cyclodextrin community gathers in Dunkerque to share thoughts, and results, discuss collaborations and renew friendships.
From CarboHyde‘s perspective, there are several lectures that we look forward to with great excitement:
And this is just the tip of the iceberg.
