We are the proudest, when students we mentor flourish and grow.
Fahad Khan Tareen, PhD spent a short time this year at CarboHyde, so we dont take the merits for his excellent science, but hope the insights we gave can contibute to his career.
Congratulations on your PhD!
We wish you the best, and dont dare to move away from cyclodextrins 🙂
We are happy and proud to finally announce that CarboHyde won a 2024-1.2.7-EUROSTARS-2025-00007 grant and shall receive ~190,000k Eur to develop a novel cyclodextrin-based Alzheimer asset.
The novel mechanism of action focuses on cholesterol modulation in this neurodegenerative disease and will aim to complete most IND enabling preclinical studies so that regulatory filings and clinical studies can begin shortly.
Recently I had the chance to sit down with Louise Jefferies on her podcast Speaking up in English at Work for Introverts – and it turned into one of the most honest conversations I’ve had about science, communication, and the fears many of us quietly carry.
My main message was simple: Scientists are doing extraordinary work behind the scenes… but far too much of it never reaches the people who need it.
In the episode, we talked about something I see every day in our field: most scientists stay silent — not because they lack expertise, but because they doubt whether their voice matters. And that silence costs the industry more than we realise.
We unpacked a lot, including • why publishing papers is no longer enough • how misinformation fills the void when experts hold back • the visibility challenges introverts and multilingual scientists face • the fear of posting, presenting, or speaking up (and why our imagined catastrophes almost never happen) • why LinkedIn is actually one of the safest, kindest spaces to start sharing • and how having a purpose makes fear feel a lot smaller
If there’s one thing I hope listeners take away, it’s this: Your work can influence decisions, shape policy, and move our field forward — but only if your voice is heard.
You don’t need to be louder. You don’t need to perform. You just need to stop hiding expertise that genuinely matters.
If you’ve ever hesitated to post, present, or speak up in a meeting, this conversation might be exactly what you need.
Before Christmas, we presented the “exam” of the cyclodextrin masterclasses. The contestants competed online, facing 30 questions about cyclodextrins to find out who is the king of cyclodextrins.
Not only were the event and all the masterclasses fun to deliver, but Shima’s message also warmed our hearts dearly:
“I would like to sincerely thank you, for the excellent masterclasses and for all the support you provide. The sessions were extremely valuable and truly enhanced my understanding of cyclodextrins.
I also wanted to share that I placed first in the online competition . It was a great experience, and it would not have been possible without the quality of the training and materials you provided.
Thank you again for your dedication, knowledge sharing, and continuous support. It is greatly appreciated.”
Exciting research is emerging around α-cyclodextrin (ACD) and its potential role in supporting key aspects of athletic performance.
Traditionally recognized for its unique molecular structure and digestive benefits, ACD is now being explored for targeted applications in sports and human performance.
A recent invention highlights how formulations containing ACD may help support: • Physical strength and endurance • Reduced feelings of fatigue • Improved exercise comfort through moderated heart-rate response • A healthier gut environment, including the proliferation of Bacteroides uniformis, an important member of the intestinal microbiome
What makes ACD particularly compelling is its versatility, ease of oral administration, and favorable safety profile. The research suggests that consistent daily intake over a period of at least seven days may be key to unlocking these benefits.
As interest in microbiome-centric performance solutions grows, ACD is shaping up to be an intriguing candidate for future innovation in nutrition, wellness, and athletic optimization.
The intersection of gut health and performance continues to expand—and ACD may be one of the ingredients helping to bridge that gap.
1. Be informed about possibilities The range of cyclodextrins you can use in pharma / nutra / cosmetic products are very different – always understand the full range that you can pick from
2. Check the administration route The regulatory status – especially in pharma – of the CDs differs. Depending on the admin route you pick, the applicable CDs will be shortlisted
3. Focus on your purpose and the active There are over a dozen technologies that you can use to create a cyclodextrin complex. Which one you pick should be driven by the characteristics of the active and further processing of the complex
4. Don’t think binary Cyclodextrin complexation is a sensitive equilibrium that you can influence to your advantage. Many additives can stabilize the complex and help you achieve a higher encapsulation rate and a reduction of cyclodextrin content.
5. Optimize Once you understand all the components, there are still many aspects of the formulation that favor the complex formation. Temperature, pH, and counterions may all play a crucial role here.
Let’s discuss the details so that you can create the best possible product.
Last week, Kyoto hosted the 12th Asian Cyclodextrin Conference, bringing together researchers, collaborators, and long-time friends from around the world — including several members of Bicyclos HEurope.
For us at CarboHyde, the event felt like a reunion between the two main “homes” of cyclodextrin science. Japan has long been a cradle of CD innovation, while Hungary has become another strong home driving cyclodextrins toward new applications and industries. Seeing these two hubs reconnect in Kyoto was inspiring.
Our CSO, Milo Malanga, PhD, was also present — the smiling, chatty Italian in jeans who never misses the chance to ask a sharp question after each lecture. His presence helped spark new conversations and strengthen ongoing collaborations.
The conference offered what makes this community so special: solid science, meaningful dialogue, and friendships that push the field forward.
We return from Kyoto with renewed motivation — ready to turn last week’s ideas into future cyclodextrin innovations.
We at CarboHyde are proud to see our collaboration with Allbiom – Inteligência em Bioprocessos represented at the CIFARP – International Congress of Pharmaceutical Sciences!
The joint research presented by Lilian Pontes and Amanda Brandão, under the leadership of Dr. Ana Carolina Ré, beautifully demonstrates how cyclodextrins can serve as molecular bridges between agro- and pharma-biotechnology — enabling smarter delivery systems, modulation of microbial processes, and new bioproduction strategies.
This collaboration reflects CarboHyde’s mission to expand the application horizon of cyclodextrins beyond traditional boundaries — harnessing their supramolecular chemistry to open new routes in sustainable innovation.
A big thank you to our partners at Allbiom for their scientific excellence and inspiring teamwork. We’re excited to see where this synergy will lead next!
Not sure what is going on here, but Pedro Vieira most certainly exploits all the learning potential during his GlyCanDrug MSCA-DN secondment in Budapest.
First he learned about the fluorescent labelling of cyclodextrins with Milo and now he is trained by Balazs in formulating his insoluble sugars – again, with cyclodextrins.