Using CDs in variuous fields of drug delivery is getting more attention; here is a new application: CD-supported nanoparticles to carry intact CRISPR/CAS9 proteins by University of California, Los Angeles (Hsian-Rong Tseng, Qian Ban, zhu yazhen, Peng Yang)
A great review on a unique industrial application: Green β-cyclodextrin-based corrosion inhibitors from National University of Uzbekistan, University of South Africa/Universiteit van Suid-Afrika, Ibn Tofail University, Yeungnam University and Sidi Mohamed Ben Abdellah University
Lyle Isaacs and his team from University of Maryland has something fascinating to show. Not only have they published a potent supramolecular host for in vivo sequestration of methamphetamine and fentanyl (similar to the Sugammadex concept) but they also shared this cool video on the mechanism of action: UMD Researcher Creates Chemical Compound That Can Reverse Effects of Potentially Deadly Drugs – YouTube
This is how you should present science! Amazing!
Adam Brockett, Canjia Zhai, Shivangi Rastogi, Volker Briken
Cool carbohydrates chemistry to make cyclodextrin dimers presented by Charles University (Konstantin Lebedinskii, Volodymyr Lobaz and Jindřich Jindřich)
In this creative paper Sven Stegemann, Amrit Paudel (Technische Universität Graz), Chris Moreton (FinnBrit Consulting), Sami Svanbäck (The Solubility Company), Karl Box (Pion Inc.), and Genevieve Motte (JEN Pharma Consulting) analyze trends in oral drug product development.
See the full article here or read the pdf below
I am bringing an economic, environmental, and green chemistry application today: Desulfurization of biodiesel produced from waste fats, oils, and grease using β-CD by Cong Liu, Anthony Provatas and Richard Parnas from the University of Connecticut.
Great learning opportunity presented by Ajay Semalty on CD complexes in general. Here you can learn about CD chemistry and basic properties and techniques to make complexes, and analyze them shown in several practical examples. Extremely informative!
Please share and spread the word.
Fascinating cyclodextrin conjugation chemistry from Southwest Jiaotong University in order to target the hydroxyapatite component of the bone. We are also highly involved in conjugating peptides and carbohydrates to create actives and drug delivery systems. Have you ever considered a peptide-CD conjugate for such an application?
Science masterpiece by Università degli Studi di Milano-Bicocca – Laura Russo, who presents the development of a 3D printed colorectal cancer model discovering that hyaluronic acid and gelatin glycosylation influences the construct morphology, and protein profiles of tumoroid cells
Mindblowing study!
See the full article here
Milo Malanga and Tamas Sohajda delivered a talk during the annual seminar of the “drug substance analysis” group of the Hungarian Academy of Sciences yesterday. We are grateful for the invitation and stimulating discussion that followed the presentation.
