Training hard? Consider taking some ACD with your creatine

Exciting research is emerging around α-cyclodextrin (ACD) and its potential role in supporting key aspects of athletic performance.

Traditionally recognized for its unique molecular structure and digestive benefits, ACD is now being explored for targeted applications in sports and human performance.

A recent invention highlights how formulations containing ACD may help support:
• Physical strength and endurance
• Reduced feelings of fatigue
• Improved exercise comfort through moderated heart-rate response
• A healthier gut environment, including the proliferation of Bacteroides uniformis, an important member of the intestinal microbiome

What makes ACD particularly compelling is its versatility, ease of oral administration, and favorable safety profile. The research suggests that consistent daily intake over a period of at least seven days may be key to unlocking these benefits.

As interest in microbiome-centric performance solutions grows, ACD is shaping up to be an intriguing candidate for future innovation in nutrition, wellness, and athletic optimization.

The intersection of gut health and performance continues to expand—and ACD may be one of the ingredients helping to bridge that gap.

carbohyde training

Hidden cyclodextrin innovations

Last week at the EuroCD-25, I talked about how the innovation landscape is changing in the cyclodextrin field.

What was dominated by pharma 20-30-40 years ago is getting taken over by non-pharma these days.

New derivatives (like polymers or conjugates) and innovative drug delivery solutions (like MOFs) emerge and get commercialized in cosmetic, environmental, household and nutraceutical uses.

My talk was not only describing the case studies but also analyzing what was the key to their success, what enabled them to be successful in the market.

In your opinion – what is the key for successful innovation?

Who loves ironing?

I do, but still curious about this product containing hydroxypropyl-beta cyclodextrin.

Bid wrinkles adieu.

According to the description:
Simply spray it on your fabric, give it a quick tug, and its unique formula lets you smooth away unsightly wrinkles in seconds.
Not to mention it adds a light, fresh scent that leaves you feeling smoother, too.

Similarly to Febreeze, the cyclodextrin magic is claimed to be odor removal, not wrinkle smoothening.

Too bad, would have loved that.

Optimizing 6-benzylaminopurine for micropropagation: A cyclodextrin monomers and polymers approach

What a personal milestone!

Our youngest one, Dani Bisericaru was still at Università degli Studi di Torino when he did this work that now led to his first first-author paper.

Special gratitude goes to Francesco Trotta and Adrián Matencio Durán for their excellent mentorship of Dani that we enjoy to this very day at CarboHyde.

So check out and learn how this research lays the foundation of the eco-friendly use of cyclodextrin-based polymers for micropropagation improvement.

Optimizing 6-benzylaminopurine for micropropagation: A cyclodextrin monomers and polymers approach – ScienceDirect

The protective effect of cyclodextrin on the color quality and stability of Cabernet Sauvignon red wine

Do you enjoy wine? Enjoy it better with cyclodextrin!

The weekend is almost here, so it’s time to enjoy some wine – with CDs, of course!

From this paper, you can learn about the protective effect of the post-fermentation addition of CDs on the color stability of red wine from the viewpoints of color characteristics, pigmentation, and phenolic profiles.

The evolution of anthocyanin form and the content of monomeric anthocyanins revealed that β-CD is a superior favorable cofactor during wine aging. Still, for long-term aging, 2-HP-β-CD and 2-HP-γ-CD are more beneficial in promoting the formation of polymerized anthocyanins and color stability.

The protective effect of cyclodextrin on the color quality and stability of Cabernet Sauvignon red wine – ScienceDirect

Cyclodextrin Magic: Safely Revitalize Your Hair Color with Cutting-Edge Technology

What a fascinating cyclodextrin application from L’Oréal. Formulations of a reducing agents and a cyclodextrins are proposed for removing color from keratin fibers such as hair.

This invention underlines the vast potential of CDs in cosmetic applications. If you would like to learn how you can develop a CD-based product yourself, this is the best place to look: Formulation development – www.carbohydesolutions.com

Link to patent: US20240197599 COMPOSITIONS AND METHODS FOR REMOVING COLOR FROM HAIR (wipo.int)