CarboHyde CEO Tamas Sohajda Presents at CPHI NA on Novel Uses of Cyclodextrins in the Pharmaceutical Industry

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CarboHyde CEO Tamas Sohajda recently delivered a compelling presentation at the CPHI North America conference, focusing on innovative applications of cyclodextrins in the pharmaceutical industry. His talk highlighted how these unique cyclic oligosaccharides can enhance drug delivery, improve solubility, and stabilize formulations, offering significant benefits to pharmaceutical development.

Cyclodextrins, known for their ability to form inclusion complexes with various molecules, have been extensively studied for their potential to revolutionize drug formulations. Sohajda’s presentation delved into recent advancements and case studies demonstrating the successful integration of cyclodextrins in new drug delivery systems. These developments promise to improve the efficacy and safety of numerous medications, addressing longstanding challenges in drug formulation and bioavailability.

The talk received considerable attention from industry professionals, underscoring CarboHyde’s leading role in pioneering the use of cyclodextrins for pharmaceutical innovation. Attendees had the opportunity to engage with Sohajda, discussing cyclodextrin research’s practical applications and future directions.

A video of the event is available on CPHI website – after a registration – for those who missed the presentation or wish to revisit the insights shared.

CPHI: Lightning Round: Excipients 4.0 – Cyclodextrins (CDs) (video) (cphi-online.com)

On Vimeo:

Dr Tamas Sohajda Lightning Round Excipients 4.0 – Cyclodextrins CDs on Vimeo

Stay tuned for more updates from CarboHyde as they continue to push the boundaries of pharmaceutical technology.

How was the 21st International Cyclodextrin Symposium?

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Last week between 10-14 June, the cream of cyclodextrin science gathered in Dunkerque, France to share their knowledge and most recent scientific results during the 21st International Cyclodextrin Symposium.

The conference started with a social tour, visiting nearby sights on the seashore and harbor and spending a wonderful lunch together. We concluded the first-day networking with a welcome party at the Town Hall.

ICS 2024, CarboHyde, Dunkerque

During the event, we could enjoy 81 oral presentations spread across a 3 and half-day scientific fiesta. 166 participants from all around the world (75% Europe, 15% Asia, 10% America) exchanged ideas and initiated collaborations. The most well-represented countries were France, Italy, and Hungary (:P).

During the breaks, we could enjoy bites from French cuisine and discuss further science through the 56 presented posters.

CarboHyde, ICS 2024, Genegut
Caitriona O’Driscoll from UCC giving her keynote

The 1st day was topped by a huge Dunkerque beer&cheese carnival, one of the most memorable social events of all time, while the 2nd one with a wonderful Gala dinner at the stunning nearby aquarium.

ICS 2024, CArboHyde,
Bicyclos team at the Dunkerque Carnival

CarboHyde was represented by two members, Daniel Bisericaru and Tamas Sohajda, and presented a talk about the status, future and dilemmas of developing cyclodextrin-based active ingredients. Further collaborations of the company were dominated by sharing the results of two EU-funded projects: GENEGUT & Bicyclos HEurope.

Several awards were presented during the Symposium:

  • the prestigious Szejtli award went to Sophie Beeren for her groundbreaking work on novel enzymatic methods to create cyclodextrins
  • the best poster award to Ana Francisca Soares from Genegut on CD-based gene delivery
  • the best flash presentation to Martina Dragone discussing peptide-CD interactions
  • the best oral presentation to Clara Testard presenting high-level cyclodextrin synthesis

The conference was concluded by sharing future events where professionals can meet again:

  • Francesco Trotta will organize a CD Summer school in June, 2025 in Geneva, mainly for students
  • The next EUROCD will be held in Milano, September, 2025 as shown by Andrea Mele
  • Keiichi Motoyama invited attendees to Kyoto for the next Asian CD conference to be held in November, 2025.

I hope to see many of you during these events!

It was an amazing experience, huge thanks to the organizers Sophie Fourmentin, Eric MONFLIER and Bernard Martel for their excellent work.

Best wishes, Tamas

Few days to go until 21st International Cyclodextrin Symposium

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In a few days the global cyclodextrin community gathers in Dunkerque to share thoughts, and results, discuss collaborations and renew friendships.

From CarboHyde‘s perspective, there are several lectures that we look forward to with great excitement:

  1. Francesco Stellacci – our long time collaborator from EPFL , pioneer of using cyclodextrins as antiviral compounds, founder of asterivir
  2. Matthew “Oki” O’Connor – CEO of Cyclarity Therapeutics , a close partner of us doing groundbreaking science of using CDs in atherosclerosis
  3. Tamas Sohajda – CarboHyde CEO delivers a review on using cyclodextrins as active ingredients
  4. Julien Parcq & Damien TRUFFIN – from Roquette, our key partner in cyclodextrin education, discussing critical attributes of CD manufacturing & safety
  5. Milo Malanga PhD – CarboHyde CSO sharing from synthetic challenges
  6. Juan Manuel Benito – Bicyclos HEurope partner, expert in using CDs for gene delivery
  7. Caitriona O’Driscoll – GENEGUT coordinator, an expert in using CDs for gene delivery
  8. Francesco Trotta & Adrián Matencio Durán, our research partners on nanosponges from University of Turin
  9. Szabolcs Béni – from CarboHyde advisory board and BiCyclos member from Eötvös Loránd University, an expert on CD NMR and analysis
  10. Ilse Manet – BiCyclos coordinator, an expert in CD analysis and applications

And this is just the tip of the iceberg.

21st International Cyclodextrin Symposium, Carbohyde

Captions of EuroCD 2023

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A week ago, we were bathing in cyclodextrin science in Budapest at the 7th European Cyclodextrin Symposium. As usual, the well-organized event was mainly dominated by European attendees, yet we also met fellows from Japan and the United States too.

Cyclodextrin manufacturers were represented by Roquette, WACKER, Ligand Pharmaceuticals and Cyclolab R&D Ltd. (the organizer, of course) and I was happy to see several companies focusing on developing cyclodextrin-based therapeutics, such as Beren Therapeutics, Cyclarity Therapeutics, ASDERA and CarboHyde.

During the 2,5 days we enjoyed 9 sessions of various topics:

  1. Cyclodextrin production & enzymology
  2. Synthesis of CD derivatives
  3. Cyclodextrin complexes and self-assembly
  4. CDs in drug delivery
  5. Biological effects of CDs
  6. CDs in gene delivery
  7. Environmental applications
  8. Analysis, application in sensing and imaging
  9. Agri-food applications

We had sessions for short presentations and could enjoy 67 posters during the breaks.

Personally, the presentations I found most interesting from academia were

At CarboHyde, we contributed to 6 oral talks and several posters highlighting our active involvement in both industrial and academic cyclodextrin research.

My takeaway is that the event was fantastic, especially due to the great conversations we could enjoy during discussions, breaks, and social events via the joint contribution to our community.

See you all in Dunkerque on the 10th June, 2014 at the International event!

I am really excited already, as Sophie Fourmentin showed great effort to invite CD cyclodextrins from all over the world, so this will truly be a global event. I would be extremely happy if not only global academia, but global pharma with all the several dozen CD users would be present to set good directions for the future of cyclodextrin research.

Dóra Ujj presentation at the Therapeutical Purposes Research and Development Congress at the University of Debrecen

drug delivery

Dóra Ujj (Budapest University of Technology and Economics) presents the results of her collaboration with Milo Malanga Ph.D., Szabolcs Béni, Gábor Benkovics Ph.D. and Tamas Sohajda, among others on analytical and therapeutic applications of Sugammadex analogs at the Therapeutical Purposes Research and Development congress at University of Debrecen.
Thank you for the great organization, if you are close, you should try to attend the 2nd day of the even today with more lectures on cyclodextrin, drug delivery, and pharmaceutical technology.

If you are interested in the details, you can also read the paper published on the topic.