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Tag: toxicity

Testing Serum Albumins and Cyclodextrins as Potential Binders of the Mycotoxin Metabolites Alternariol-3-Sulfate, Alternariol-9-Monomethylether and Alternariol-9-Monomethylether-3-Sulfate

Nov 22, 2022Tamas SohajdaToday's cyclodextrinfood&beverage, toxicity

Interesting study on mycotoxin binding CDs and serum albumin and their potential uses in food analysis delivered by the University of Pécs Medical School (POTE formerly) – and Cyclolab

Read the full article here


Inclusion Solves Insolubility —Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C

Oct 21, 2022Tamas Sohajdadrug developmentcholesterol, rare disease, toxicity, translational research

Tetsumi Irie form Kumamoto University explains the differences in the mechanisms of action for HPBCD and HPGCD in the treatment of Niemann-Pick C.

Full article: https://doi.org/10.1248/yakushi.21-00215

Testing the Protective Effects of Sulfobutylether-Βeta-Cyclodextrin (SBECD) and Sugammadex against Chlorpromazine-Induced Acute Toxicity in SH-SY5Y Cell Line and in NMRI Mice

Sep 16, 2022Tamas Sohajdadrug discoverytoxicity, toxicology

Yet another novel use proposed for sugammadex and SBE-cyclodextrin: as antidotes against chlorpromazine-induced acute toxicity. An excellent paper by Eszter Nyúl, Rita Klaudia Csepregi, Gábor Benkovics PhD, Lajos Szente, and Poór Miklós from the University of Pécs.

For more details, follow this link.

sugammadex, SBECD, carbohyde

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