Cyclodextrin-based polyrotaxanes and protein hybrids as three-dimensional printing inks

Today's cyclodextrin,

today’s cyclodextrin:
we have already talked about both rotaxanes and CD-supported 3D printing Now Dartmouth College, an invention form Chenfeng Ke; Qianming Lin; Miao Tang and Li Longyu presents the combination of the two.
Rotaxanes have numerous applications, including applications in three-dimensional printing. However, current rotaxanes have numerous limitations in terms of fabrication and properties optimal for 3D printing. For instance, the synthesis of cyclodextrin-based three-dimensional (3D)—printable polypseudorotaxanes, which are formed by threading α-cyclodextrins (α-CDs) onto linear polyethylene glycol (PEG), requires the use of high molecular weight PEG with a minimal molecular weight of 10 k Pa.
Rotaxanes presented in this patent overcome such handicaps and offer a feasible solution.

See the full patent here on Espacenet

Direct cyclodextrin-based powder extrusion 3D printing of budesonide-loaded mini-tablets for the treatment of eosinophilic colitis in pediatric patients

Today's cyclodextrin, , ,

Have you ever wondered how cyclodextrins fit into modern, fancy formulation technologies like 3D printing? Nunzio Denora and his group at Università degli Studi di Bari and Institute of Crystallography – CNR show how to make budesonide-loaded mini-tablets using direct cyclodextrin-based powder extrusion 3D printing.

Monica Pistone, Giuseppe Francesco Racaniello, rosanna rizzi, Rosa Maria Iacobazzi, Ilaria Arduino, Antonio Lopalco, Angela Assunta Lopedota

See the full article here