Analysis of Peptides and Proteins by Native and SDS Capillary Gel Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry via a Closed-Circuit Coaxial Sheath Flow Reactor Interface

today’s cyclodextrin:
CD-supported capillary gel electrophoresis analysis of proteins and peptides including SDS–protein complexes, by Dániel Sárközy and Andras Guttman from the University of Debrecen. Addition of γ-cyclodextrin to the sheath liquid efficiently removed the SDS content of the sample and the background electrolyte in the flow reactor section by inclusion complexation, while maintaining good separation efficiency and decreasing ion suppression.


See the full article here