Silylated-Acetylated Cyclodextrins as Chiral Sensors for the Enantiodiscrimination of Fluorinated Anesthetics

Today's cyclodextrin,

today’s cyclodextrin:
is a nice piece of research from a collaboration between Università di Pisa and CarboHyde‘s CSO, Milo Malanga investigating the use of silylated-acetylated cyclodextrins as #chiral #sensors for the enantiodiscrimination of fluorinated anesthetics

Alessandra Recchimurzo, Federica Balzano, Gloria Uccello Barretta, Luca Gherardi and Federica Aiello

See the full article here: Silylated-Acetylated Cyclodextrins as Chiral Sensors for the Enantiodiscrimination of Fluorinated Anesthetics

Fully Symmetric Cyclodextrin Polycarboxylates: How to Determine Reliable Protonation Constants from NMR Titration Data

carbohydrates,

We are happy to share the most recent paper of Milo Malanga Ph.D. on acid-base properties of cyclodextrin, particularly Sugammadex and its analogs developed together with Semmelweis University (Szabolcs Béni, Eszter Kalydi), Richter Gedeon Nyrt. / Magyarország (Zoltán Szakács), Gábor Benkovics PhD and Dóra Ujj.
The pH-dependent charge of these compounds can now be accurately calculated in support of designing new analytical methods to exploit their charge-dependent molecular recognition, such as in cyclodextrin-aided chiral capillary electrophoresis.