We are fond of developing advanced drug delivery solutions, including targeted precision systems. In this patent, you can find a great approach to such a process by combining cyclodextrin with Galnac for liver targeting.
Liver-targeted drug delivery carrier as well as preparation method and application
We are hearing a lot about how the cholesterol complexation ability of certain cyclodextrins, especially hydroxypropyl-beta-CD can be used to treat various diseases, like Alzheimer’s, Niemann Pick type C, atherosclerosis, familial hypercholesterolemia and many more.
But can this be a double-edged sword? This fascinating research suggests that High-Cholesterol Diet in Combination With Hydroxypropylβ-Cyclodextrin Induces NASH-Like Disorders in the Liver of Rats
You can read the full article here!
today’s cyclodextrin:
Not entirely new, yet very important invention by
Daniel Wils and Caroline PERREAU from Roquette: methyl cyclodextrin is presented in the treatment and/or prevention of hepatic steatosis and related diseases via reduced lipid accumulation in the liver.
You can view the complete patent on Espacenet.
