Formulation and investigation of differently charged β-cyclodextrin-based meloxicam potassium containing nasal powders

drug development, Today's cyclodextrin

Today’s cyclodextrin is a nice formulation study from one of the best Hungarian pharmaceutical universities, the University of Szeged, who study various excipients – CDs among others – that have an important role in nasal formulations to increase the permeability of the mucosa and prolong the residence time of the drug.

The charged cyclodextrin-based formulations showed significantly higher adhesive force values regardless of the presence of PVA. The drug release was fast and complete, and the permeation of meloxicam was enhanced.

Patricia Varga, Anett Németh, Scarlett Zeiringer, Eva Roblegg, Budai-Szűcs Mária, Csilla Balla-Bartos, Rita Ambrus

Formulation and investigation of differently charged β-cyclodextrin-based meloxicam potassium containing nasal powders – ScienceDirect

Kit for preparing a medicament, cannabinoid composition, and preparation method

drug delivery, , ,

today’s #cyclodextrin:
Vayamed Cannakits® hits the markets: novel formulation kits enabling a cannabis-enriched Nasal Spray, and Vaginal/Rectal Suppositories is now available. This innovation makes Vayamed the first cannabis company in Germany to expand the therapy spectrum with new dosage forms.
Depending on the final formulation, the kit contains an excipient mixture composed of vegetable oil, hydroxylated fat, and 2-hydroxypropyl-β-cyclodextrin or polyethylene glycol stearate.
Marco Ternelli – Sanity Group

See the full patent on Espacenet