Evidence of redox imbalance and mitochondrial dysfunction in Niemann-Pick type C 1 patients: the in vitro effect of combined therapy with antioxidants and β‐cyclodextrin nanoparticles
This research contributes to a better understanding of the mechanism of action of #cyclodextrin in Niemann Pick C, which could lead to further applications. Carmen Vargas – Federal University of Rio Grande do Sul evaluated naked and nanoparticle CDs for restoring mitochondrial functions, as well as the beneficial combined effects of treatment with antioxidant N-Acetylcysteine and Coenzyme Q10
Tatiane Hammerschmidt, Bruna Donida, Jéssica Lamberty Faverzani, Fernanda Poletto, Dinara Jaqueline Moura
