Posing with our brand new labmate
He will make contract works much faster at CarboHyde and support our pipeline development without complain.
Of course, the guys will not let me touch it, but that is better for all of us probably 🙂
Excited to represent CarboHyde at the DDF Summit in Berlin!
Our Lead Formulation Expert, Balázs Attila Kondoros, will be attending the upcoming Drug Delivery & Formulation (DDF) Summit in Berlin, where he’ll be diving into the latest innovations in drug delivery technologies.
At CarboHyde, we are particularly interested in exploring how emerging challenges in formulation and delivery could be addressed using cyclodextrins — unlocking new possibilities for solubility, stability, and bioavailability.
Balazs is looking forward to connecting with fellow experts, exchanging ideas, and identifying collaboration opportunities.
Do you want to learn more about Carbo and cyclodextrins?
Who else will be attending? Let’s connect in Berlin!
Interior Editing via Dynamic Molecular Recognition
Not often do I say this, but I have encountered something intriguing in cyclodextrin chemistry.
While I am not a synthesis expert, this development is remarkable.
Despite decades of research in synthetic chemistry and materials sciences, the selective editing of chemical bonds within molecular containers like cyclodextrins remains a significant challenge.
Recent findings reveal that quinuclidine, a catalyst capable of reversibly binding to the cavity of α-cyclodextrin, can selectively abstract hydrogen atoms from one of its endo C–H bonds upon single-electron oxidation. This process causes the geminal hydroxyl group to flip to the interior face of the macrocycle.
The endo-hydroxylated α-cyclodextrin has demonstrated the ability to separate chiral compounds that its natural counterpart could not resolve in gas chromatography, thanks to its desymmetrized cavity and polar recognition site.
For further details, refer to the publication: https://lnkd.in/dtBTDFy6
Who is who at CarboHyde?
Our cyclodextrin specialty company could not flourish without the amazing talents we have on the team.
But who is who and what are they doing?
We would like to bring all folks closer to you, not only who are more active on social media. From left to right:
Tamás Vargadi, COO: Tamas is handling big projects at CarboHyde that involve CDMOs, CRO and other external partners. He is also responsible for our food supplement product line and general quality matters.
Tamas Sohajda, CEO, let’s skip this one 🙂
Janka Juhász, researcher: Janka has a double role in the company, she handles the internal coordination of several national and international grants (including our website) and learns into coming a formulation scientist.
Balázs Attila Kondoros, senior scientist: Balazs leads our formulation team, he coordinates several partnered projects at all times while works on developing fascinating pipeline ideas too.
Milo Malanga PhD CSO: our cyclodextrin chemistry wizard. Milo is a widely known and acknowledged expert in CD synthesis with unlimited create ideas and pragmatic innovations. His fascination is research and pipeline, yet also helps in medicinal chemistry challenges for our partners
Gergely Toth, CFO: as the only one with an economic degree, Gergely helps the company to stay on the ground amidst all the science and dreaming. He handles all financial, legal and administrative tasks at CarboHyde while actively seeks opportunities for strategic growth.
Who are not in the picture:
Mihaly Balint, R&D director: Misi is mainly active in the synthetic lab and specializes in industrialization of chemical processes. We often deal with translational science: bringing lab scale procedures to industrial level, often under GMP. This is his field
Kristóf Felegyi, scientist: Kristof is our jolly joker, the only one that has strong expertise in chemistry, analysis and formulation with cyclodextrins. He handles both internal and external projects and complex challenges with this interdisciplinary skillset.
Szejtli Gabriella, HR: Gabi is responsible for keeping us sound and sane and guards our mental health while we guard the health of others with progressive cyclodextrin innovation.
Cyclodextrin – retinol complex
Retinol is one of the most powerful actives in skincare—but also one of the most challenging to formulate.
In this short deck, we explore how cyclodextrin complexation can unlock better retinol performance by addressing its biggest formulation hurdles:
• Improved chemical stability against oxidation, UV, and heat
• Reduced irritation risk through controlled, gradual release
• Maintained bioavailability via reversible complexation
• Simpler formulation systems compared with traditional encapsulation approaches
The result: better tolerability, sustained activity, and improved commercial viability for retinol-based products.
Curious how it works in practice?
Take a look at the full deck 👇
2nd Bicyclos HEurope workshop
Just last week, some members of the closer (Milo Malanga PhD and Mihaly Balint) and larger (Szabolcs Béni) CarboHyde team attended the 2nd Bicyclos HEurope workshop and annual gathering.
Our grant is progressing well, sharing knowledge and experience among the fantastic members under the scope of this MSCA Staff Exhange grant has been really rewarding.
See you all in 2027 in Budapest, if not sooner 😉
AI will write your grant proposal
Sounds exciting and dangerously misleading.
What generative AI can realistically do in scientific research is find relevant papers when connected to real databases, accelerate structured summaries and cross-paper comparisons, and polish rough drafts into precise, evidence-based language. What it cannot do is guarantee that a single citation it generates actually exists.
At the 2nd Bicyclos HEurope International School and Workshop in Sevilla, our very own Milo Malanga PhD delivered a hands-on session on the responsible use of generative AI in literature search, analysis and proposal writing, putting five major AI platforms to the test with a deliberately fabricated citation request. Some tools generated complete references to authors, journals, and DOIs to a paper that was never written, while others searched real databases and returned only verified sources.
The difference between a hallucinated DOI in your MSCA proposal and a verified one is not a minor detail; it is a credibility risk that can undermine months of work.
AI is a powerful accelerator for research workflows, but verification is not optional, IP protection is not an afterthought, and critical thinking is not something we can afford to outsource.
Speed matters, but accuracy matters more.
Have you ever caught an AI-generated citation that turned out to be completely fabricated? We’d love to hear how you’re navigating AI in your research workflow.
One eye smiles – one eye cries
After several beautiful years together, Daniel Bisericaru has grown out his cavity in Budapest and leaves (obviously only temporarily) CarboHyde and Hungary.
Dani was probably the most diligent among us, with an insatiable appetite for knowledge and challenge.
Wherever your road may lead you, your next place will be lucky to have you.
You are always our guest for a chimney cake and a fruit soup in Budapest 🙂
From 2026, at CarboHyde we decided to expand beyond cyclodextrin-based drug-development.
From 2026, at CarboHyde we decided to expand beyond cyclodextrin-based drug-development.
This short 2-pager captures the support we can provide locally in Hungary:
1. Drug substance development and manufacturing
2. Drug product development
3. Analytical support and CMC
4. Bioanalytical testing and toxicology
5. GMP production
6. Regulatory support
The 3 pillars of CarboHyde’s contractual support for cyclodextrins:
– custom synthesis
– formulation development
– analysis (of cyclodextrins and their complexes).
Learn more from Dani’s creation and get in touch if you have a problem to chat about in this field.