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  • Listen to the Carbohydrate Chronicles Podcast!
    • - Carbohydrate Chronicles Season 2 / Ep 1 Application beyond pharma
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CarboHyde
  • Home
  • Cyclodextrin Masterclass VII – Cyclodextrin basics
  • About Us
  • Pipeline
  • CarboHyde’s Blog
  • News
  • Listen to the Carbohydrate Chronicles Podcast!
    • Carbohydrate Chronicles Season 2 / Ep 1 Application beyond pharma
    • Carbohydrate Chronicles Season 2 / Ep 2 Cyclodextrin in biologic formulation
    • Carbohydrate Chronicles Season 2 / Ep 3 Safety and toxicity
    • Carbohydrate Chronicles Season 2 / Ep 4 Cyclodextrin in food and nutraceuticals
    • Carbohydrate Chronicles Season 2 / Ep 5 Cyclodextrins to improve sport performance
    • Carbohydrate Chronicles Season 2 / Ep 6 Cyclodextrins in 3D printing
    • Carbohydrate Chronicles Season 2 / Ep 7 Cyclodextrin complex in the making

Mannosylated glycans impair normal T-cell development by reprogramming commitment and repertoire diversity

Jun 26, 2023Tamas Sohajdacarbohydratesinflammation, T cells

Mannosylated glycans impair normal T-cell development.
Gabriel Rabinovich, Salomé S. Pinho et al. discovered stage-specific glycome compositions during T-cell development in human and murine thymocytes, as well as dynamic alterations. In conclusion, mannosylated thymocytes lead to a dysregulation in T-cell development that is associated with inflammation susceptibility.

See the full article here on nature.com!

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