Another important paper on cyclodextrin-assisted gene therapy from the GENEGUT consortium leader University College Cork (Caitriona O’Driscoll) now proposing a sialic acid-targeted cyclodextrin-based nanoparticle to specifically deliver CSF-1R siRNA to M2 macrophages. This targeted cyclodextrin-based siRNA drug delivery system provides a potential strategy for prostate cancer immunotherapy.
Monique Mendonça, Jianfeng Guo et al