It is fascinating how similar concepts can be used for entirely different purposes in drug delivery: while we use amphiphilic cyclodextrin for packaging oligonucleotides in the GENEGUT project, Erem Bilensoy and her team at Hacettepe University created camptothecin-loaded nanoparticles to treat colon cancer. The overall findings indicated that the strategy of orally targeting anticancer drugs such as CPT with positively charged poly-β-CD-C6 nanoparticles to colon tumors for local and/or systemic efficacy is promising.
Dr. SEDAT ÜNAL (PharmD/PhD), Gamze Varan, Yeşim Aktaş
