An important review of the hallmarks of neurodegenerative diseases for like-minded researchers who deal with this challenging field. The framework can serve as a basis for defining pathogenic mechanisms, categorizing different NDDs based on their primary hallmarks, stratifying patients within a specific NDD, and designing multi-targeted, personalized medicine to halt NDDs effectively.
Thank you for this excellent compilation!
Hasselt University/National Institute Of Aging/KU Leuven/Washington University in St. Louis/University of Gothenburg – David M Wilson III, Mark Cookson, Ludo Van Den Bosch, Henrik Zetterberg, David Holtzman, Ilse Dewachter