Today’s cyclodextrin:
is about the birth of these compounds. I collected two great sources; first, a review that presents a comprehensive view of CGTase produced by Bacillus spp. and other bacterial genera like Klebsiella, Paenibacillus, and Microbacterium. It also gives insight of the properties and recent biotechnological applications of cyclodextrins.

Cyclodextrin glucanotransferase: fundamentals and biotechnological implications | SpringerLink

However, the bioproduction of CDs still faces challenges in terms of optimization and process complexity. The 2nd study proposes a novel CD bioproduction system in a batch mode to increase yield and reduce costs. Scale-up to the bioreactor displayed improved growth kinetics for both bacteria and higher protein production and CGTase activity for Paenibacillus macerans.

Future Pharmacology | Free Full-Text | Design of a Cyclodextrin Bioproduction Process Using Bacillus pseudofirmus and Paenibacillus macerans (