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Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis

Oct 11, 2022Tamas Sohajdadrug delivery, drug developmentcardiovascular, cholesterol

The cyclodextrin-supported atherosclerosis treatment field is getting crowded. Here is a unique approach using polyethylene glycol succinate (TPGS)-CD, which was adsorbed on rHDL, then modified with Apo-Ai, and coated with hyaluronan to obtain HT-rHDL. Piece of cake!
China Pharmaceutical University

Full article on ScienceDirect
https://doi.org/10.1016/j.carbpol.2022.119632

cholesterol, carbohyde
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