Topical drug delivery with CDs seems straightforward, even with the extra advantage that CDs can contribute not only as solubilizers but also as permeation enhancers. Still, despite cosmetics, very few products are on the market.
The nano gel concept by Università degli Studi di Firenze (Marzia Cirri, Giulia Nerli, Natascia Mennini, Francesca Maestrelli, and Paola Mura) may open some new doors in this area.