How about a case study now?From bacterial toxin to long-acting pain relief
Challenge: Chronic & neuropathic pain still largely rely on short-acting, addictive opioids.
Innovation: A β-cyclodextrin polymer that encapsulates mycolactone, turning an insoluble, UV-sensitive molecule into a stable, aqueous formulation.
Chemistry: Crosslinked β-CD forms multiple host–guest cavities, solubilising and protecting mycolactone without organic solvents.
Impact: In vivo, the pCD–mycolactone combo delivers strong, long-lasting analgesia from a single injection — a promising non-opioid alternative for difficult-to-treat pain.
Check out the patent in comments if you like the idea of Ruxandra Gref; Isabelle Marsollier and Estelle Marion. We do so!
Espacenet – LONG-ACTING PAIN-RELIEF FORMULATION
Would you like to design a similar polymer for you application? Let us know, we can help.
