education - CarboHyde

Cyclodextrins – 5 tips for formulators

Dec 11, 2025adminToday's cyclodextrin, educationcarbohyde, cyclodextrin, education

1. Be informed about possibilities
The range of cyclodextrins you can use in pharma / nutra / cosmetic products are very different – always understand the full range that you can pick from

2. Check the administration route
The regulatory status – especially in pharma – of the CDs differs. Depending on the admin route you pick, the applicable CDs will be shortlisted

3. Focus on your purpose and the active
There are over a dozen technologies that you can use to create a cyclodextrin complex. Which one you pick should be driven by the characteristics of the active and further processing of the complex

4. Don’t think binary
Cyclodextrin complexation is a sensitive equilibrium that you can influence to your advantage. Many additives can stabilize the complex and help you achieve a higher encapsulation rate and a reduction of cyclodextrin content.

5. Optimize
Once you understand all the components, there are still many aspects of the formulation that favor the complex formation. Temperature, pH, and counterions may all play a crucial role here.

Let’s discuss the details so that you can create the best possible product.

Richard Tóth had a summer interns at CarboHyde

Aug 8, 2025adminnewscarbohyde, education

At CarboHyde, education and knowledge-sharing around cyclodextrins is one of our core pillars.

Whether it’s through webinars, conference presentations, or collaborative research, we believe in making science accessible and engaging.

But what we enjoy most is when we get to share our expertise in person — like welcoming summer interns to our team! Richárd Tóth from Zsombor Kristof Nagy‘s group at FirePharma Research Group BME is one of the best materials we have had so far.

These hands-on experiences not only support the next generation of scientists but also bring fresh energy and new perspectives into our lab.

Richard’s own words:

“What its like to work at CarboHyde?

I have been an intern for three weeks since late June.

In my first week, I was nervous about the unknown, but I received a warm welcome from the members of the Carbohydrate. I feel appreciated and accepted in this environment.

They involve me in a bunch of both formulations and the marketing process. I enjoy several kinds of tasks, problem-solving, and searching through the literature for some important data as well.

My favourite part of the job so far, when I had to gather up a huge amount of data about cyclodextrin-based metal-organic frameworks (CD-MOF). It was needed by a potential business partner. I learnt a lot about CD-MOFs.

All in all, I adore working here because of the friendly and supportive atmosphere. Thank you so much.”

Cyclodextrin MasterClass VI

May 21, 2025adminnews, educationcarbohyde, cyclodextrin, education, masterclass

Join us for Cyclodextrin MasterClass VI by CarboHyde, where we explore the cutting-edge developments in cyclodextrin-based oral drug formulations.

https://www.carbohyde.com/cyclodextrin-masterclass-vi-oral-formulations/

This session will delve into the design principles, marketed products, and real-world case studies that highlight the unique advantages of cyclodextrins in improving solubility, stability, and bioavailability. Whether you’re in formulation, regulatory, or pharmaceutical R&D, this MasterClass offers insights from concept to commercialization.