CarboHyde Cyclodextrin Masterclass X – Cyclodextrins as Active Ingredients
The upcoming CarboHyde Cyclodextrin Masterclass will focus on the emerging role of cyclodextrins (CDs) as active pharmaceutical ingredients (APIs), highlighting how these versatile molecules are moving beyond their classical excipient role into the therapeutic spotlight. Through landmark examples such as Sugammadex, a CD-based neuromuscular blockade reversal agent, and hydroxypropyl-β-cyclodextrin (HPβCD) in the treatment of Niemann-Pick Type C disease, participants will gain insight into how the unique host–guest chemistry of CDs translates into clinical efficacy.
The session will further explore next-generation applications of CDs, including their use as scavengers for drug overdose, and their potential in new therapies for widespread conditions such as Alzheimer’s disease and atherosclerosis, as well as rare diseases including Kabuki syndrome and focal segmental glomerulosclerosis (FSGS). The discussion will cover mechanistic aspects—how CDs modulate biological pathways and molecular interactions—alongside chemical design strategies, drug discovery approaches, and regulatory and Chemistry–Manufacturing (CM) considerations essential for translation into approved therapies.
This Masterclass will provide researchers, developers, and industry professionals with a comprehensive perspective on cyclodextrins as therapeutic agents, bridging molecular innovation with real-world drug development challenges and opportunities.
Register now – before it’s too late to uncover how cyclodextrins are redefining therapeutics!
