Present: Sugammadex can be used to reverse rocuronium and similar NMBA.
The future: Alfaxalone?
This rat study shows that Sugammadex can reverse the anesthetic effects of alfaxalone.
Recovery speed from alfaxalone anesthesia is dependent upon sugammadex dose and sex.
Obviously, its not working as well as for the original target (Compared to saline controls, sugammadex shortened recovery times by 40%–60% following anesthesia induction) but the repurposing idea is nice.
What do you think? Can a scavenger like this be repurposed for other applications?
Use of Sugammadex to Reverse Alfaxalone Anesthesia in Rats – ScienceDirect
