This time our flourishing GENEGUT collaboration produced a great paper on the SAR investigations of cyclodextrins in gene delivery.

This topic is essential to understand how cyclodextrins actually work when encapsulating different oligos and what are the ideal structures for the nanoparticle formation loading and transfection.

Got your attention?

Huge admiration to our collaborators, Ayse Kont, PhD, Monique Mendonca, PhD, Andrew Lindsay, Michael Cronin, Mary Cahill and Caitriona O’Driscoll

And last but not least, our team members, Milo and Kristóf.

The impact of cyclodextrin architecture and charge for optimized nucleic acid delivery: A comparison of monomers, dimers, and polymers – ScienceDirect