What a bright day for our company!
We have a new PhD among us, huge congratulations to Kristóf Felegyi (and maybe his wife, Csenge Anna Felegyi-Tóth :P) to a successful defense!
Summary of the PhD thesis:
The dissertation investigates the chemical composition and biological activities of Buglossoporus quercinus and Xylobolus subpileatus.
- B. quercinus: Identified novel and known polyporenic acids. Some compounds showed moderate antiproliferative effects on colon cancer cells and inhibited the P-glycoprotein efflux pump. Synergistic interactions with doxorubicin were observed.
- X. subpileatus: Isolated seven compounds, including a new natural product (XB-1). Some metabolites exhibited enzyme inhibition, with XB-3 showing strong antityrosinase activity and XB-3/4 inhibiting AChE and BChE.
The findings suggest potential applications in cancer treatment and enzyme inhibition.
Also this means that now 50+% of our fantastic team has PhD! Not bad…
