Berberine – a plant alkaloid with antimicrobial, anti-inflammatory, and metabolic health benefits – faces poor solubility and bioavailability.
Cyclodextrins – cyclic oligosaccharides with a hydrophobic cavity – can encapsulate berberine, improving its aqueous solubility and stability.
Synergistic boost: Inclusion complexes enhance berberine’s absorption and therapeutic potential in gut health, metabolic regulation, and infection control.
Formulation flexibility: Cyclodextrin–berberine systems can be adapted for oral, topical, or nanoparticle-based delivery.
Innovation pathway: This pairing bridges traditional botanical medicine with modern delivery science for more effective, patient-friendly solutions.
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