Today’s cyclodextrin is about a pan-respiratory antiviral that can transform clinical management and be a key tool for pandemic preparedness.
A novel modified cyclodextrin mimicking sialic acid & heparan sulfate shows broad-spectrum antiviral activity.
Respiratory viruses can cause severe infections, including bronchiolitis and pneumonia, often leading to hospitalization or death. Due to their ease of transmission, they are also scrutinized for their pandemic potential. No broad-spectrum antiviral is currently available.
Maybe a cyclodextrin can be the key.
Fantastic paper by old friends Paulo Jacob Silva, Francesco Stellacci and collaborators.
