VI International Summer School on Cyclodextrins

The VI International Summer School on Cyclodextrins, held in Genoa, Italy, brought together young scientists and leading experts under the theme “Natural molecules for a better life”. Hosted in the historic surroundings of the University of Genoa, the event kicked off with impactful keynote lectures by Dr. Milo Malanga (CarboHyde) on sustainable and scalable cyclodextrin synthesis, and Prof. Li (National University of Singapore) on supramolecular cyclodextrin assemblies for drug and gene delivery.

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The summer school served as a vibrant platform for PhD students and early-career researchers to present their work, such as on thermosensitive intranasal gels, amino-acid functionalized CDs, and other drug delivery systems — via posters and flash oral presentations. Participants appreciated not only the scientific value but also the strong networking opportunities and the support of mentors like Milo Malanga and Prof. Sorrenti.

CarboHyde Cyclodextrin Masterclass VII – Cyclodextrin Basics

In order to receive the link to join, you have to register at the external CarboHyde link of the event too.

Join us for the 7th Cyclodextrin Masterclass by CarboHyde, where we dive into the fascinating world of cyclodextrins—cyclic oligosaccharides with unique capabilities that have revolutionized pharmaceutical, food, and cosmetic applications.

In this introductory session, we’ll revisit the origins of cyclodextrins, their distinctive ring-shaped structures, and how these features enable them to form host–guest complexes with a wide range of molecules. Whether you’re new to the field or seeking a structured refresher, this webinar will provide a clear, concise foundation in cyclodextrin science.

We’ll explore how cyclodextrins behave in various environments, their physicochemical properties, and why their safety profile makes them ideal for diverse formulation challenges. Join us to understand the core principles behind these versatile molecules—and set the stage for deeper insights in the sessions to follow

Cyclodextrins in 3D printing

Step into a world where medicine meets the future — and transforms it.

In this episode, discover how cyclodextrins, a powerful yet underrated class of molecules, are revolutionizing 3D and 4D printing in biomedicine.

From shape-shifting drug delivery systems to personalized pediatric mini-tablets, these sustainable compounds are driving breakthroughs in targeted treatment, tissue repair, and more.

Tune in to explore how cyclodextrins are reshaping the very fabric of healthcare.

(14) Cyclodextrins in 3D printing | LinkedIn

Cyclodextrins in 3D printing

The retinol-loaded microneedles

Today’s cyclodextrin is about microneedles.

Cyclodextrins are emerging as valuable excipients in microneedle-based drug delivery systems due to their unique ability to form inclusion complexes with a wide range of therapeutic molecules, and the fact that such complexes can often form microneedles on their own.

By enhancing the solubility, stability, and bioavailability of drugs, cyclodextrins improve the efficiency of transdermal delivery through microneedles and can also facilitate the controlled release of active ingredients, offering a promising strategy for the delivery of poorly water-soluble compounds or sensitive biomolecules.

Incorporating cyclodextrins into microneedle matrices or coatings enables targeted, minimally invasive therapies with potential applications in vaccination, pain management, and chronic disease treatment.

And a recent, real-world example? Check out how Raphas is using CDs to stabilize retinol-loaded microneedles and achieve high transdermal delivery efficiency, thus maximizing the effect of retinol on wrinkle reduction.

Espacenet – US2025143986A1 COMPOSITION FOR MICRONEEDLE PREPARATION, COMPRISING CYCLODEXTRIN FOR RETINOL STABILIZATION, AND MICRONEEDLE PREPARED WITH SAME COMPOSITION