Do you enjoy wine? Enjoy it better with cyclodextrin!
The weekend is almost here, so it’s time to enjoy some wine – with CDs, of course!
From this paper, you can learn about the protective effect of the post-fermentation addition of CDs on the color stability of red wine from the viewpoints of color characteristics, pigmentation, and phenolic profiles.
The evolution of anthocyanin form and the content of monomeric anthocyanins revealed that β-CD is a superior favorable cofactor during wine aging. Still, for long-term aging, 2-HP-β-CD and 2-HP-γ-CD are more beneficial in promoting the formation of polymerized anthocyanins and color stability.
Not many things get better with years passing but some do. Things like: – whiskey, – wine – blue jeans – friendships and Thorsteinn Loftsson
This was my first thought when reading this paper, which I coauthored with Hay Man Saung Hnin Soe and Phatsawee Jansook on cyclodextrin-based nanoparticles.
This review emphasizes the role of cyclodextrins (CDs) in stabilizing colloidal nanoparticles (NPs) and improving drug solubility. The integration of CDs with NPs offers a synergistic strategy that enhances drug delivery and expands the scope of biomedical applications. Furthermore, the review thoroughly explores the potential of CDs to boost the stability and therapeutic effectiveness of colloidal NPs, positioning them as promising candidates for advanced drug delivery systems
Event Overview: Join us for an illuminating webinar that traces the evolution of cyclodextrin-based drug delivery systems—from laboratory research to real-world patient care. Our esteemed speakers will explore key aspects of this journey, highlighting breakthroughs, challenges, and the promise of cyclodextrins in improving therapeutic outcomes.
Agenda:
Preparation of Parenteral and Oral Cyclodextrin-Based Formulations and Their Physical Characterization
Speaker: Dr. Carmen Popescu (Roquette)
Dr. Popescu will unveil the meticulous process of formulating cyclodextrin-based drugs for parenteral and oral administration. From solubility enhancement to stability studies, discover how cyclodextrins bridge the gap between lab experiments and clinical applications.
Cyclodextrins in Liquid, Transdermal, and Other Non-Traditional Forms
Speaker: Dr. Balazs Kondoros (CarboHyde)
Dr. Kondoros will guide us beyond conventional dosage forms. Explore how cyclodextrins revolutionize liquid formulations, transdermal patches, and other innovative delivery methods. Witness the transition from theoretical concepts to practical solutions.
Hunting for Cyclodextrins: Analytical Assay Methods in Biological Fluids
Speaker: Dr. Tamas Sohajda (Carbohyde)
Dr. Sohajda’s presentation focuses on the detective work involved in studying cyclodextrins within biological matrices. Learn about cutting-edge assay techniques, their role in clinical trials, and the critical insights they provide.
Promising Future for HPBCD in Inhalation
Speaker: Dr. Natacha Rocks (Aquilon)
Dr. Rocks will unveil the exciting prospects of hydroxypropyl-β-cyclodextrin (HPBCD) in inhalation therapies. From lung-targeted drug delivery to patient-friendly devices, witness how cyclodextrins are poised to transform respiratory medicine.
Today’s cyclodextrin is another clinical study showing the benefits of using alpha-cyclodextrin to improve exercise performance and reduces post-exercise fatigue.
α-Cyclodextrin (αCD), a cyclic hexasaccharide composed of six glucose units, is not digested in the small intestine but is completely fermented by gut microbes.
αCD supplementation significantly improved endurance exercise performance (10 km biking time trial) compared with the placebo.
The heart rate increase was lower in the αCD group than in the placebo group during exercise.
On Day 1, we started with with students sharing results and plans from their secondments, then moved along to hear from PIs about challenges, possibilities and wishes regarding the project.
Day 3-4 was a mix of science and soft skills with analytical lectures (Ilse Manet and Szabolcs Béni) and cyclodextrins in electrosensors (Maria Antonietta Casulli). The last sessions of the workshop dealt with soft skills rather than science. Tamas Sohajda shared insights of using social media and AI for making science more accessible. Then Ilse Manet, Maria Antonietta Casulli and Barbara Ventura delivered a workshop about grantwriting.
